The paper assesses the environmental benefits of using self-dispensing systems for liquid detergents in Italian retail stores, where consumers refill containers instead of using single-use plastic bottles. A life cycle assessment (LCA) compared these systems to traditional packaging for various detergents, focusing on waste reduction, energy demand, and environmental impacts. Results show that self-dispensing systems can reduce waste by up to 98% and decrease energy use and environmental impacts, with greater benefits seen as containers are reused more frequently.