The hot-spot analysis is intended as an environmental meta-study and focuses on alternative options for e-commerce with the aim of identifying possible strategies for improvement/areas for innovation to reduce packaging impacts. This report investigates single-use (SU) and multiple-use (MU) packaging solutions. These two solutions could be made of different materials (e.g., corrugated board, plastic bags, rigid plastic crates, paper bags, flexible packaging). The main focus of this analysis is the e-commerce supply chain, such as information related to online shops (and platforms), automatisation of processes, digital purchasing, shipping of products, as well as other relevant aspects, such as product damage, packaging void, empty load transport, logistics, return transport or weight of the packaging.